Dr Fernanda Cisneros Soberanis
Postdoctoral Research Fellow
Dr Fernanda Cisneros Soberanis joined Earnshaw lab in September 2017 as a Postdoctoral Research funded by CONACyT (Mexico).
Fernanda undertook her undergraduate studies in a specialist program for biomedical research at UNAM (the most prestigious university in Latin America), which was designed to prepare the next generation of scientist to develop innovative projects in biomedical sciences. In 2012, Fernanda began her PhD under the supervision of Dr Luis Alonso Herrera, a collaboration between UNAM and the National Cancer Institute in Mexico. During her PhD, she studied the transcriptional regulation of microRNAs in breast cancer.
In 2017, Fernanda joined Earnshaw lab attracted by the Human Artificial Chromosome model. Then, Bill convince her to learn electron microscopy to study chromosome structure during mitosis. Currently, she is characterising the function of the chromosome periphery in mitosis (by light and electron microscopy) and helping other members in the lab preparing samples for electron microscopy and 3D reconstruction.
Martins NMC, Cisneros-Soberanis F, Pesenti E, Kochanova NY, Shang WH, Hori T, Nagase T, Kimura H, Larionov V, Masumoto H, Fukagawa T, Earnshaw WC (2020), H3K9me3 maintenance on a human artificial chromosome is required for segregation but not centromere epigenetic memory, J Cell Sci, 133(14): jcs242610.
Saldivar JC, Hamperl S, Bocek MJ, Chung M, Bass TE, Cisneros-Soberanis F, Samejima K, Xie L, Paulson JR, Earnshaw WC, Cortez D, Meyer T, Cimprich KA (2018), An intrinsic S/G 2 checkpoint enforced by ATR, Science, 361 (6404): 806-810.
Cisneros-Soberanis F, Andonegui MA, Herrera LA (2016), miR-125b-1 is repressed by histone modifications in breast cancer cell lines, Springerplus, 5(1): 959.
Andonegui-Elguera MA, Cáceres-Gutiérrez RE, Luna-Maldonado F, López-Saavedra A, Díaz-Chávez J, Cisneros-Soberanis F, Prada D, Mendoza-Pérez J, Herrera LA (2016), BUB1 and SURVIVIN proteins are not degraded after a prolonged mitosis and accumulate in the nuclei of HCT116 cells, Cell Death and Discov, 2: 16079.
Soto-Reyes E, González-Barrios R, Cisneros-Soberanis F, Herrera-Goepfert R, Pérez V, Cantú D, Prada D, Castro C, Recillas-Targa F, Herrera LA (2012), Disruption of CTCF at the miR-125b1 locus in gynecological cancers, BMC Cancer, 12:40.