Projects

Forming chromosomes

earnshaw-lab-projects

What are the principal structural and biochemical events that drive chromosome formation as cells enter mitosis?

Lab Members involved

Coating chromosomes

earnshaw lab projects

How do nucleolar proteins and RNAs assemble the mitotic chromosome periphery compartment and is this important?

Lab Members involved

Segregating chromosomes

Projects 23

How is centromere chromatin assembled, organised and disassembled during mitosis on an endogenous vertebrate chromosome and during human artificial chromosome (HAC) formation? 

Lab Members involved

Controlling the process

Ruchaud CPC Metaphase, Anaphase

How do mitotic kinases, including Cdk1 and Aurora B in the Chromosomal Passenger Complex (CPC), regulate events during synchronous entry and exit from mitosis?

Lab Members involved