Carmena, M., S. Ruchaud and W.C. Earnshaw. (2009). Making the Auroras glow: Regulation of Aurora A and B kinase function by interacting proteins. Curr. Opin. Cell Biol. 21: 796-805. PMID: 19836940DOI: 10.1016/; FREE ARTICLE

Xu, Z., H. Ogawa, J.H. Bergmann, P. Vagnarelli, D.F. Hudson, S. Ruchaud, T. Fukagawa, W.C. Earnshaw and K. Samejima. (2009). INCENP-Aurora B interactions modulate kinase activity and chromosome passenger complex localization. J. Cell Biol. 187: 637-653. PMID: 19951914DOI: 10.1083/jcb.200906053; FREE ARTICLE

Cardinale, S., J.H. Bergmann, D. Kelly, M. Nakano, M.M. Valdivia, H. Kimura, H. Masumoto, V. Larionov and W.C. Earnshaw. (2009) Hierarchical inactivation of a synthetic human kinetochore by a chromatin modifier. Mol. Biol. Cell 20: 4194-4204. PMID: 19656847; PMC2754933; DOI: 10.1091/mbc.E09-06-0489; FREE ACCESS

Ribeiro S.A., J.C. Gatlin, Y. Dong, A. Joglekar, L. Cameron, D.F. Hudson, C.J. Farr, B.F. McEwen, E.D. Salmon, W.C. Earnshaw, and P. Vagnarelli. (2009) Condensin Regulates the Stiffness of Vertebrate Centromeres. Mol. Biol. Cell 20: 2371-2380. PMID: 19261808; PMC2675617; DOI: 10.1091/mbc.E08-11-1127; FREE ARTICLE

Zhou L, J. Li, R. George, S. Ruchaud, HG Zhou, J.E. Ladbury, W.C. Earnshaw, X. Yuan (2009). Effects of Full-Length Borealin on the Composition and Protein-Protein Interaction Activity of a Binary Chromosomal Passenger Complex. Biochemistry 48: 1156-1161 PMID: 19146389; PMC2746994; DOI: 10.1021/bi801298j ; FREE ARTICLE

Hudson, D.F., K.M. Marshall and W.C. Earnshaw. (2009) Condensin: Architect of Mitotic Chromosomes. Chromosome Res. 17: 131-144. PMID: 19308696; DOI: 10.1007/s10577-008-9009-7 ARTICLE

Vagnarelli, P., S. Ribeiro and W.C. Earnshaw. (2008). Centromeres: old tales and new tools. FEBS Letts. 582:1950-1959. PMID: 18435926; DOI: 10.1016/j.febslet.2008.04.014 FREE ARTICLE  

Yue, Z., A. Carvalho, Z. Xu, X. Yuan, S. Cardinale, S. Ribeiro, F. Lai, H. Ogawa, E. Gudmundsdottir, R. Gassmann, C.G. Morrison, S. Ruchaud and W.C. Earnshaw. (2008). Deconstructing Survivin: Comprehensive genetic analysis of Survivin function by conditional knockout in a vertebrate cell line. J. Cell Biol. 183: 279-296. PMID: 18936249; PMC2568024; DOI: 10.1083/jcb.200806118; (Faculty of 1000) FREE ARTICLE

Tadeu, A.M.B., S. Ribeiro, J. Johnston, I. Goldberg, D. Gerloff and W.C. Earnshaw. (2008). CENP-V is required for centromere organisation, chromosome alignment and cytokinesis. The EMBO J. 27: 2510-2522. PMID: 18772885; PMC2532784; DOI: 10.1038/emboj.2008.175; FREE ARTICLE  

Colombié N., C.F. Cullen, A.L. Brittle, J.K. Jang, W.C. Earnshaw, M. Carmena, K. McKim and H. Ohkura. (2008). Dual roles of Incenp critical to the assembly of the acentrosomal metaphase spindle in female meiosis. Development, 135: 3239-3246. PMID: 18755775; PMC2536564; DOI: 10.1242/dev.022624; FREE ARTICLE

Hudson,D.F. S. Ohta, T. Freisinger, F. MacIsaac, L. Sennels, F. Alves, F. Lai, A. Kerr, J. Rappsilber, and W.C. Earnshaw. (2008). Molecular and genetic analysis of condensin function in vertebrate cells. Mol. Biol. Cell 19:3070-3079. PMID: 18480406 PMC2441691; DOI: 10.1091/mbc.E08-01-0057 (see also Molecular Biol. Cell 19: 2681, InCytes) FREE ARTICLE

Nakano, M.*, S. Cardinale*, V.N. Noskov, R. Gassmann, P. Vagnarelli, S. Kandels-Lewis, V. Larionov, W.C. Earnshaw and H. Masumoto. (2008). *equal first authors. equal corresponding authors. Inactivation of a human kinetochore by specific targeting of chromatin modifiers. Dev. Cell 14,507-522. PMID: 18410728; PMC2311382; DOI: 10.1016/j.devcel.2008.02.001 (Faculty of 1000; see also Nature Revs. Molecular Cell Biology 9: 351); FREE ARTICLE

Kaufmann,S.H., S.-H. Lee, X.W. Meng, D.A. Loegering, T.J. Kottke, A.J. Henzing, S. Ruchaud, K. Samejima, and W.C. Earnshaw. (2008) Apoptosis-Associated Caspase Activation Assays. Methods 44: 262-272. PMID: 18314058; DOI: 10.1016/j.ymeth.2007.11.005  ARTICLE

Samejima, K. H. Ogawa, C.A. Cooke, D.F. Hudson, F. Maclsaac, S.A. Ribeiro, P. Vagnarelli, S. Cardinale, A. Kerr, F. Lai, S. Ruchaud, Z. Yue and W.C. Earnshaw. (2008). A promoter-hijack strategy for conditional shutdown of multiply spliced essential cell cycle genes. Proc. Nat. Acad. Sci. (USA) 105: 2457-2462. PMID: 18263736; PMC2268158; DOI: 10.1073/pnas.0712083105; FREE ARTICLE

Griffith E., S. Walker, C.-A. Martin, P. Vagnarelli, T. Stiff, B. Vernay, N. Al Sanna, A. Saggar, B. Hamel, W.C. Earnshaw, P.A. Jeggo, A.P. Jackson, M. O’Driscoll. (2008). Mutations in Pericentrin cause Seckel syndrome with defective ATR-dependent DNA damage signalling. Nat. Genet. 40:232-236. PMID: 18157127; PMC2397541; DOI: 10.1038/ng.2007.80; (Faculty of 1000) FREE ARTICLE

Ruchaud, S., M. Carmena and W.C. Earnshaw. (2007). The Chromosomal passenger complex: One for all and all for one. Cell 131: 230-231 (see also Nature Revs. Molecular Cell Biology 8: 944) PMID: 17956723; DOI: 10.1016/j.cell.2007.10.002; FREE ARTICLE

Ruchaud S., M. Carmena and W.C. Earnshaw. (2007). Chromosomal passengers: Conducting cell division. Nature Revs. Mol. Cell Biol. 8: 798-812. PMID: 17848966; DOI: 10.1038/nrm225 ARTICLE

Toné, S., K. Sugimoto, K. Tanda, T. Suda, K. Uehira, H. Kanouchi, K. Samejima, Y. Minatogawa and W.C. Earnshaw. (2007). Three distinct stages of apoptotic nuclear condensation revealed by time-lapse imaging, biochemical and electron microscopy analysis of cell-free apoptosis. Exp. Cell Res. 313: 3635-3644. PMID: 17643424; PMC2705844; DOI: 10.1016/j.yexcr.2007.06.018; FREE ARTICLE

Ageichik, A.V., K. Samejima, S.H. Kaufmann, and WC. Earnshaw. (2007). Genetic analysis of the short splice variant of the inhibitor of caspase-activated DNase (ICAD-S) in chicken DT40 cells. J. Biol. Chem. 282: 27374-27382. PMID: 17616520; DOI: 10.1074/jbc.M704307200; FREE ARTICLE

Faragher, A.J., X.-M. Sun, M. Butterworth, N. Harper, S. Ruchaud, W.C. Earnshaw and G.M. Cohen (2007). Death receptor induced apoptosis reveals a novel interplay between the chromosomal passenger complex and CENP-C during interphase. Mol. Biol. Cell 18: 1337-1347. PMID: 17287400; PMC1838999; DOI: 10.1091/mbc.E06-05-0409; FREE ARTICLE

Zachos, G., E.J. Black, M. Walker, M. Scott, P. Vagnarelli, W.C. Earnshaw and D.A.F. Gillespie. (2007). Chk1 is required for spindle checkpoint function. Dev. Cell 12:247-260. PMID: 17276342; DOI: 10.1016/j.devcel.2007.01.003 (Faculty of 1000) FREE ARTICLE

Rodriguez-Bayona, B, S. Ruchaud, C. Rodriguez, M. Linares, A. Astola, M. Ortiz, W.C. Earnshaw and M. Valdivia. (2007). Autoantibodies against the chromosomal passenger protein INCENP found in a patient with Graham Little-Piccardi-Lassueur syndrome J. Autoimmune Dis. 4:1. PMID: 17222351; PMC1783653; DOI: 10.1186/1740-2557-4-1; FREE ARTICLE

Ruchaud, S., K. Samejima, D. Hudson, S.H. Kaufmann and W.C. Earnshaw. (2006). Genetic Analysis Of Apoptotic Execution, in Reviews and Protocols In DT40-Research, J.M Buerstedde and S. Takeda, Eds., Springer, N.Y., pp. 75-90. Listed in PubMed as: Subcell Biochem. 40:75-90. PMID: 17623901 DOI: 10.1007/978-1-4020-4896-8_6 ARTICLE

Earnshaw, W.C. and Y.A. Lazebnik (2006). Cell division, growth and death. Editorial overview. Curr. Opin. Cell Biol. 18:587-588. DOI: 10.1016/ ARTICLE

Carmena M. & W.C. Earnshaw (2006). INCENP at the kinase crossroads. Nat. Cell Biol. 8:110-111. PMID: 16450006; DOI: 10.1038/ncb0206-110 ARTICLE

Henzing, A.J., H. Dodson, J.M. Reid, S.H. Kaufmann, R.L. Baxter and W.C. Earnshaw. (2006) Synthesis of Novel Caspase Inhibitors for Characterization of the Active Caspase Proteome in Vitro and in Vivo. J. Med. Chem. 49:7636-7645. PMID: 17181147; PMC2564993; DOI: 10.1021/jm060385h; FREE ARTICLE

Vagnarelli, P., D.F. Hudson, S.A. Ribeiro, L. Trinkle-Mulcahy, J.M. Spence, F. Lai, C.J. Farr, A.I. Lamond and W.C. Earnshaw. (2006). Condensin and Repo-Man/PP1 co-operate in the regulation of chromosome architecture during mitosis. Nat. Cell Biol. 8: 1133-1142. PMID: 16998479; PMC2741681; DOI: 10.1038/ncb1475; FREE ARTICLE

Pereira, A.L., A.J. Pereira, A.R.R. Maia, K. Drabek, C.L. Sayas, P.J. Hergert, M. Lince-Faria, I. Matos, C. Duque, T. Stepanova, C.L. Rieder, W.C. Earnshaw, N. Galjart, and H. Maiato. (2006). Mammalian CLASP1 and CLASP2 cooperate to ensure mitotic fidelity by regulating spindle and kinetochore function Mol. Biol. Cell17:4526-4542. PMID: 16914514; PMC1635371; DOI: 10.1091/mbc.E06-07-0579; FREE ARTICLE

Resnick T.D., D.L. Satinover, F. MacIsaac, P.T. Stukenberg, W.C. Earnshaw, T.L. Orr-Weaver, & M. Carmena (2006) INCENP and Aurora B Promote Meiotic Sister Chromatid Cohesion through Localization of the Shugoshin MEI-S332 in Drosophila. Dev. Cell,11:57-68. PMID: 16824953; DOI: 10.1016/j.devcel.2006.04.021; FREE ARTICLE

Heale, J.T. A.R. Ball, Jr., J.A. Schmiesing, J.-S. Kim, X. Kong,1 S. Zhou, D. Hudson, W.C. Earnshaw, and K. Yokomori. (2006) Condensin I interacts with the PARP-1-XRCC1 complex and functions in DNA single-stranded break repair. Mol. Cell, 21:837-848. PMID: 16543152; DOI: 10.1016/j.molcel.2006.01.036 (Faculty of 1000) FREE ARTICLE

Chang, C.-J. S. Goulding, R.R. Adams, W.C. Earnshaw and M. Carmena. (2006) Drosophila INCENP is required for cytokinesis and asymmetric cell division during development of the nervous system. J. Cell Sci.119:1144-1153. PMID: 16507586; DOI: 10.1242/jcs.02834; FREE ARTICLE

Earnshaw, W.C. (2005). Keeping survivin nimble at centromeres in mitosis. Science310:1443-1444. PMID: 16322445; DOI: 10.1126/science.1121952 ARTICLE

Goulding, S.E. and W.C. Earnshaw. (2005). Shugoshin: A centromeric guardian senses tension BioEssays 27:588-591. PMID: 15892113; DOI: 10.1002/bies.20240 ARTICLE

Earnshaw, W.C. and M. Gatti. (2005). Chromosome Segregation and Aneuploidy: introducing a new series in Trends in Cell Biology. Trends Cell Biol. 15, 229-230. DOI: FREE ARTICLE

LoegeringD.A., S. Ruchaud, W.C. Earnshaw and Scott H. Kaufmann (2005) Evaluation of the Role of Caspase-6 in Anticancer Drug-Induced apoptosis. Cell Death Diff. 13, 346-347. PMID: 16294214; DOI: 10.1038/sj.cdd.4401791; FREE ARTICLE

Samejima, K. and W.C. Earnshaw. (2005) Trashing the genome: The role of nucleases during apoptosis. Nature Revs. Mol. Cell Biol. 6: 677-688. PMID: 16103871; DOI: 10.1038/nrm1715; ARTICLE

Régnier, V. P. Vagnarelli, T. Fukagawa, T. Zerjal, E. Burns, D. Trouche, W.C. Earnshaw and W. Brown. (2005) CENP-A is required for accurate chromosome segregation and sustained kinetochore association of BubR1 Mol. Cell. Biol. 25: 3967-3981. PMID: 15870271; PMC1087704; DOI: 10.1128/MCB.25.10.3967-3981.2005; FREE ARTICLE

Nagata Y, Jones MR, Nguyen HG, McCrann DJ, St Hilaire C, Schreiber BM, Hashimoto A, Inagaki M, Earnshaw WC, Todokoro K, K. Ravid. (2005). Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp. Cell Res. 305: 277-291. PMID: 15817153; DOI: 10.1016/j.yexcr.2004.12.028; ARTICLE

Gassmann R, A.J. Henzing and W.C. Earnshaw (2005) Novel components of human mitotic chromosomes identified by proteomic analysis of the chromosome scaffold fraction. Chromosoma. 113:385-397. PMID: 15609038; DOI: 10.1007/s00412-004-0326-0; ARTICLE

Sasai, K., H. Katayama, D.L. Stenoien, S. Fujii, R. Honda, M. Kimura, Y. Okano, M. Tatsuka, F. Suzuki, E.A. Nigg W.C. Earnshaw, W.R. Brinkley and S. Sen. (2004). Aurora-C kinase is A Novel Chromosomal Passenger Protein That Can Complement Aurora-B kinase Function in Mitotic Cells Cell Motil. Cytoskel. 59: 249-263. PMID: 15499654; DOI: 10.1002/cm.20039; ARTICLE

Maiato, H., J. DeLuca, E.D. Salmon and W.C. Earnshaw. (2004). The dynamic kinetochore-microtubule interface J. Cell Sci. 117: 5461-5477. PMID: 15509863; DOI: 10.1242/jcs.01536; FREE ARTICLE

Vagnarelli, P. & W.C. Earnshaw. (2004). Chromosomal Passengers: The Four Dimensional Regulation of Mitotic Events. Chromosoma 113: 211-222. PMID: 15351889; DOI: 10.1007/s00412-004-0307-3; ARTICLE

Dodson, H., E. Bourke, L.J. Jeffers, P. Vagnarelli, E. Sonoda, S. Takeda, W.C. Earnshaw, A. Merdes and C. Morrison. (2004). Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. The EMBO J. 23, 3864-3873. PMID: 15359281; PMC522792; DOI: 10.1038/sj.emboj.7600393; FREE ARTICLE

Kurasawa, Y., W.C. Earnshaw, Y. Mochizuki, N. Dohmae & K. Todokoro. (2004). Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation. The EMBO J, 23: 3237-3248. PMID: 15297875; PMC514520; DOI: 10.1038/sj.emboj.7600347; FREE ARTICLE

Gassmann, R., A. Carvalho, A.J. Henzing, 4, S. Ruchaud, D.F. Hudson, R. Honda, E.A. Nigg, D.L. Gerloff and W.C. Earnshaw. (2004). Borealin: A novel chromosomal passenger required for stability of the bipolar mitotic spindle. J. Cell Biol., 166: 179-191. PMID: 15249581; PMC2172304; DOI: 10.1083/jcb.200404001 (see also Nature Cell Biology 6: 692) FREE ARTICLE

Steensgaard, P., M. Garrè, I. Muradore, P. Transidico, E. Nigg, K. Kitagawa, W.C. Earnshaw, M. Faretta and A. Musacchio. (2004). Sgt1 is required for human pre-kinetochore assembly EMBO Repts. 5, 626-631. PMID: 15133482; PMC1299074; DOI: 10.1038/sj.embor.7400154 FREE ARTICLE

Gassmann R, Vagnarelli P, Hudson D, W.C. Earnshaw. (2004) Mitotic chromosome formation and the condensin paradox. Exp. Cell Res. 296: 35-42. PMID: 15120991; DOI: 10.1016/j.yexcr.2004.03.006; ARTICLE

Wheatley, S.P., A.J. Henzing, H. Dodson, W. Khaled and W.C. Earnshaw. (2004). Aurora-B phosphorylation in vitro identifies a residue of Survivin that is essential for its localization and binding to INCENP in vivo. J. Biol. Chem. 279, 5655-5660. PMID: 14610074; DOI: 10.1074/jbc.M311299200; FREE ARTICLE

Vagnarelli, P., C. Morrison, H. Dodson, E. Sonoda, S. Takeda and W.C. Earnshaw. (2004). Analysis of Scc1-deficient cells defines a key metaphase role of vertebrate cohesin in linking sister kinetochores. EMBO Repts. 5, 167-171. PMID: 14749720; PMC1298988; DOI: 10.1038/sj.embor.7400077 (Faculty of 1000); FREE ARTICLE

Korfali, N., S. Ruchaud, D. Loegering, D. Bernard, C. Dingwall, S.H. Kaufmann and W.C. Earnshaw (2004). Caspase-7 Gene Disruption Reveals an Involvement of the Enzyme During the Early Stages of Apoptosis. J. Biol. Chem. 279, 1030-1039. PMID: 14583630; DOI: 10.1074/jbc.M306277200; FREE ARTICLE

Maiato, H. C.L. Rieder, W.C. Earnshaw and C.E. Sunkel. (2003). How do kinetochores CLASP dynamic microtubules? Cell Cycle 2, 511-514. PMID: 14504462  DOI: 10.4161/cc.2.6.576 FREE ARTICLE

Morrison, C., P. Vagnarelli, E. Sonoda, S. Takeda and W.C. Earnshaw (2003). Sister chromatid cohesion and genome stability in vertebrate cells. Biochem. Soc. Trans. 31, 263-265. PMID: 12546698 DOI: 10.1042/bst0310263

Chang, C.-J., S. Goulding, W.C. Earnshaw and M. Carmena. (2003). RNAi analysis reveals an unexpected role for Topoisomerase II in chromosome congression to the metaphase plate. J. Cell Sci. 116: 4715-4726. PMID: 14600258; DOI: 10.1242/jcs.00797; FREE ARTICLE

Carmena, M. and W.C. Earnshaw. (2003) The cellular geography of Aurora kinases. Nature Revs. Mol. Cell Biol., 4: 842-854. PMID: 14625535; DOI: 10.1038/nrm1245; FREE ARTICLE

Hudson, D., P. Vagnarelli, R. Gassmann and W.C. Earnshaw. (2003). Condensin is required for non-histone protein assembly and structural integrity of vertebrate mitotic chromosomes. Dev. Cell, 5: 323-336. PMID: 12919682; DOI: 10.1016/S1534-5807(03)00199-0 (Faculty of 1000; see also Nature Revs. Molecular Cell Biology 4: 748) FREE ARTICLE

Carvalho, A. M. Carmena, Clara Sambade, W.C. Earnshaw and S.P. Wheatley. (2003). Survivin is required for stable checkpoint activation in taxol-treated HeLa cells. J. Cell Sci. 116: 2987-2998. PMID: 12783991; DOI: 10.1242/jcs.00612; FREE ARTICLE

Maiato, H., E.A.L. Fairley, C.L. Rieder, J.R. Swedlow, C.E. Sunkel and W.C. Earnshaw. (2003). Human CLASP1 Is an Outer Kinetochore Component that Regulates Spindle Microtubule Dynamics. Cell 113: 891-904. PMID: 12837247; DOI: 10.1016/S0092-8674(03)00465-3; (Faculty of 1000) FREE ARTICLE

Maiato, H., C.E. Sunkel and W.C. Earnshaw. (2003). Dissecting mitosis by RNAi in Drosophila tissue culture cells. Biol. Proced. Online 5:153-161. PMID: 14569613; PMC162172; DOI: 10.1251/bpo57; FREE ARTICLE

Cheung, W.L., K. Ajiro, K. Samejima, Mm Kloc, P. Cheung, C.A. Mizzen, A. Beeser, L.D. Etkin, J. Chernoff, W.C. Earnshaw, and C.D. Allis. (2003). Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell113:507-517. PMID: 12757711; DOI: 10.1016/S0092-8674(03)00355-6; FREE ARTICLE

Earnshaw, W.C. and M. Carmena. (2003). A perfect funeral with no corpse. J. Cell Biol. 160: 889-990. PMID: 12668654; PMC2172778; DOI: 10.1083/jcb.200303005; FREE ARTICLE

Parra, M.T., A. Viera, R. Gómez, M. Carmena, W.C. Earnshaw, J.S. Rufas and J.A. Suja. (2003). Dynamic relocalization of the chromosomal passenger complex proteins inner centromere protein (INCENP) and aurora-B kinase during male mouse meiosis. J. Cell Sci. 116: 961-974. PMID: 12584241; DOI: 10.1242/jcs.00330; FREE ARTICLE

Morrison, C., A.J. Henzing, O.N. Jensen, N Osheroff, S.E. Kandels-Lewis, R.R. Adams and W.C. Earnshaw. (2002). Proteomic analysis of human metaphase chromosomes reveals Topoisomerase II alpha as an Aurora B substrate. Nucleic Acids Res. 30:5318-5327. PMID: 12466558; PMC137976; DOI: 10.1093/nar/gkf665; FREE ARTICLE

Trazzi, S., R. Bernardoni, V. Politi, D. Diolaiti, W.C. Earnshaw, G. Perini and G. Della Valle. (2002). In vivo functional dissection of the human inner kinetochore protein CENP-C. J. Structl Biol, 140:39-48. PMID: 12490152; DOI: 10.1016/S1047-8477(02)00506-3; ARTICLE

Spence, J.M., R. Critcher, T.A. Ebersole, M.M. Valdivia, W.C. Earnshaw, T. Fukagawa and C.J. Farr. (2002) Co-localisation of centromere activity, proteins and topoisomerase II within a subdomain of the major human X a‑satellite array. The EMBO J. 21:5269-5280. PMID: 12356743; PMC129033; DOI: 10.1093/emboj/cdf511; (Faculty of 1000) FREE ARTICLE

Hudson D.F., C. Morrison, S. Ruchaud & W.C. Earnshaw. (2002). Reverse genetics of essential genes in tissue culture cells: ‘Dead cells talking’ Trends Cell Biol. 12: 281-287. PMID: 12074888; DOI: 10.1016/S0962-8924(02)02281-X; ARTICLE

Politi V., G. Perini, S. Trazzi, A. Pliss, I. Raska, W.C. Earnshaw, G. Della Valle. (2002). CENP-C binds the alpha-satellite DNA in vivo at specific centromere domains. J. Cell Sci. 115: 2317-2327. PMID: 12006616; DOI: unknown; FREE ARTICLE

Maiato, H., P. Sampaio, C.L. Lemos, J. Findlay, M. Carmena, W.C. Earnshaw and C.E. Sunkel. (2002) MAST/Orbit has a role in microtubule-kinetochore attachment and is essential for chromosome alignment and maintenance of spindle bipolarity. J. Cell Biol.: 157, 749-760. PMID: 12034769; PMC2173411; DOI: 10.1083/jcb.200201101; (Faculty of 1000) FREE ARTICLE

Ruchaud, S., N. Korfali, P. Villa, T.J. Kottke, C. Dingwall, S.H. Kaufmann and W.C. Earnshaw. (2002). Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation. The EMBO J. 21: 1967-1977. PMID: 11953316; PMC125972; DOI: 10.1093/emboj/21.8.1967; FREE ARTICLE

Nishihashi, A., T Haraguchi, Y. Hiraoka, T. Ikemura, V. Regnier, H. Dodson, W.C. Earnshaw and T. Fukagawa. (2002). CENP-I is essential for centromere function in vertebrate cells. Dev. Cell, 2: 463 – 476. PMID: 11970896; DOI: 10.1016/S1534-5807(02)00144-2; (Faculty of 1000) FREE ARTICLE

Mejia, J.E., A. Alazami, A. Willmott, P. Marschall, E. Levy, W.C. Earnshaw, Z. Larin. (2002). Efficiency of de novo centromere formation in human artificial chromosomes. Genomics 79: 297-304. PMID: 11863359; DOI: 10.1006/geno.2002.6704; ARTICLE

Kottke, T.J., A.L. Blajeski, X.W. Meng, P.A. Svingen, S. Ruchaud, P.W. Mesner, Jr., S.A. Boerner, K. Samejima, N.V. Henriquez, T.J. Chilcote, J. Lord, M. Salmon, W.C. Earnshaw and S.H. Kaufmann (2002). Lack of Correlation Between Caspase Activation and Caspase Activity Assays in Paclitaxel-Treated MCF-7 Breast Cancer Cells. J. Biol. Chem. 277: 804-815. PMID: 11677238; DOI: 10.1074/jbc.M108419200; FREE ARTICLE

Jullien, D., Vagnarelli, W.C.Earnshaw, & Y. Adachi (2002) Kinetochore localisation of the DNA damage response components 53BP1 during mitosis. J. Cell Sci. 115: 71-79. PMID: 11801725; DOI: unknown; FREE ARTICLE

Kaufmann, S.H., L.. Martins, A.J. Henzing, T.J. Kottke, and W.C. Earnshaw. (2001). Analysis of Caspase Activation During Apoptosis Current Protocols In Cell Biology(J.S. Bonifacino, M. Dasso, J.B. Harford, J. Lippincott-Schwartz and K. Yamada, eds.) John Wiley & Sons, New York, 18.2.1-18.2.29, 2001. PMID: 18228341 DOI: 10.1002/0471143030.cb1802s11 ARTICLE

Boucher, C., S. Gobeil, K. Samejima, W. Earnshaw and G.G. Poirier. (2001). Identification and analysis of caspase substrates: Proteolytic cleavage of poly(ADP-ribose)polymerase and DNA fragmentation factor 45. Methods Cell Biol. 66, 289-306. PMID: 11396007 DOI: 10.1016/s0091-679x(01)66013-8 ARTICLE

Earnshaw, W.C. (2001). Chromosomal passengers. Curr. Biol. 11: R683-R683. PMID: 11553338; DOI: 10.1016/S0960-9822(01)00407-9 ARTICLE

Sonoda, E., T. Matsusaka, C. Morrison, P. Vagnarelli, O. Hoshi, T. Ushiki, K. Nojima, T. Fukagawa, I.C.Waizenegger, J.-M. Peters, W.C. Earnshaw and S. Takeda. (2001) Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev. Cell, 1: 759-770. PMID: 11740938; DOI: 10.1016/S1534-5807(01)00088-0; (Faculty of 1000) FREE ARTICLE

Samejima, K., S. Tone and W.C. Earnshaw (2001). CAD/DFF40 nuclease is dispensable for high molecular weight DNA cleavage and stage I chromatin condensation in apoptosis. J. Biol. Chem. 276: 45427-45432. PMID: 11577114; DOI: 10.1074/jbc.M108844200; FREE ARTICLE

Vagnarelli, P. & W.C. Earnshaw. (2001). INCENP loss from an inactive centromere correlates with the loss of sister chromatid cohesion. Chromosoma 110: 393-401. PMID: 11734997; DOI: 10.1007/s004120100163; (Faculty of 1000) ARTICLE

Van Hooser, A.A., I.I. Ouspenski, H.C. Gregson, D.A. Starr, T.J. Yen, M.L. Goldberg, K. Yokomori, W.C. Earnshaw, K.F. Sullivan and B.R. Brinkley. (2001). Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J. Cell Sci. 114: 3529-3542. PMID: 11682612; DOI: unknown; FREE ARTICLE

Mejía, J.E., A. Willmott, E. Levy, W.C. Earnshaw, Z. Larin. (2001). Functional complementation of a genetic deficiency with human artificial chromosomes. Am. J. Hum. Genet. 69: 315-326. PMID: 11452360; PMC1235305; DOI: 10.1086/321977; FREE ARTICLE

Murnion, M.E., R.A. Adams, D.M. Callister, C.D. Allis, W.C. Earnshaw and J.R. Swedlow. (2001). Chromatin-associated protein phosphatase 1 regulates Aurora-B and histone H3 phosphorylation. J. Biol. Chem. 276: 26656-26665. PMID: 11350965; DOI: 10.1074/jbc.M102288200; FREE ARTICLE

Wheatley S.P, A. Carvalho, P. Vagnarelli and W.C. Earnshaw. (2001). INCENP is required for proper targeting of survivin to the centromeres and the anaphase spindle during mitosis. Curr. Biol., 11: 886-890. PMID: 11516652; DOI: 10.1016/S0960-9822(01)00238-X; FREE ARTICLE

Adams, R.R., H. Maiato, W.C. Earnshaw and M. Carmena. (2001). Essential roles of Drosophila inner centromere protein (INCENP) and Aurora-B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J. Cell Biol. 153:865-80. PMID: 11352945; PMC2192373; DOI: 10.1083/jcb.153.4.865; FREE ARTICLE

Adams, R.R., D.M. Eckley, P. Vagnarelli, S.P. Wheatley, D.L. Gerloff, A.M. Mackay, P.A. Svingen, S.H. Kaufmann and W.C. Earnshaw. (2001). Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells Chromosoma 110: 65-74. PMID: 11453556; DOI: 10.1007/s004120100130; ARTICLE

Adams, R.R. , M. Carmena & W.C. Earnshaw. (2001). Chromosomal passengers and the (aurora) ABCs of mitosis. Trends Cell Biol. 11: 49-54. PMID: 11166196; DOI: 10.1016/S0962-8924(00)01880-8; ARTICLE

Wheatley, S.P., S.E. Kandels-Lewis, R.R. Adams, A.M. Ainsztein & W.C. Earnshaw. (2001). INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow. Exp. Cell Res. 262: 122-127. PMID: 11139336; DOI: 10.1006/excr.2000.5088; ARTICLE

Kaufmann, S. H., Mesner, P. W. J., Samejima, K., Tone, S. and W.C. Earnshaw. (2000). Detection of DNA cleavage in apoptotic cells. Methods Enzymol. 322, 3-15. PMID: 10914000; DOI: 10.1016/s0076-6879(00)22003-x; ARTICLE

Earnshaw W.C., K. Samejima, F. Durrieu, J. Fortune, N. Osheroff. (2000). Biochemical mechanism of apoptotic execution. Ann Endocrinol (Paris). 61:137. PMID: 10960326

Raska, I., U. Aebi & W.C. Earnshaw. (2000). EMBO WORKSHOP REPORT: An eclipse over the cell nucleus. Functional organization of the cell nucleus. Prague, August 9-12, 1999. The EMBO J. 19: 3843-3848. PMID: 10921866; PMC306611; DOI: 10.1093/emboj/19.15.3843 FREE ARTICLE

Petruti-Mot, A. S. and W.C. Earnshaw. (2000) Two differentially spliced forms of topoisomerase IIalpha and beta mRNAs are conserved between birds and humans. Gene 258: 183-192 PMID: 11111056; DOI: 10.1016/S0378-1119(00)00465-0; ARTICLE

Sugata, N., S. Li, W.C. Earnshaw, T.J. Yen, E. Munekata, K. Yoda, H. Masumoto, P.E. Warburton & K. Todokoro. (2000). Human CENP-H multimers colocalize with CENP-A and CENP–C at active centromere-kinetochore complexes. Hum. Mol. Genet. 9: 2919-2926. PMID: 11092768; DOI: 10.1093/hmg/9.19.2919; FREE ARTICLE

Adams, R.R., S.P. Wheatley, A.M. Gouldsworthy, S.E. Kandels-Lewis, M. Carmena, C. Smythe, D.L. Gerloff & W.C. Earnshaw. (2000). INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow. Curr. Biol., 10: 1075-1078. PMID: 10996078; DOI: 10.1016/S0960-9822(00)00673-4; FREE ARTICLE

Susin, S.A., E. Daugas, K. Samejima, N. Zamzami, M. Loeffler, L. Ravagnan, K. Ferri, P. Constantini, T. Irinopoulou, M.-C. Prévost, A. Srinivasan, H. Yoshida, G. Brothers, J. Penninger, W.C. Earnshaw & G. Kroemer. (2000). Two distinct pathways leading to nuclear apoptosis. J. Exp. Med. 192: 571-580. PMID: 10952727; PMC2193229; DOI: 10.1084/jem.192.4.571; FREE ARTICLE

Floridia, A., G. Gimelli, O. Zuffardi, W.C. Earnshaw, P.E. Warburton & C. Tyler-Smith (2000). A neocentromere in the DAZ region of the human Y chromosome. Chromosoma 109: 318-327. PMID: 11007490; DOI: 10.1007/s004120000081; FREE ARTICLE

Johnson, D., M. Agochiya, K. Samejima, W. Earnshaw, M. Frame and J. Wycke. (2000). Regulation of both apoptosis and cell survival by the v-Src oncoprotein. Cell Death Diff. 7, 685-696. PMID: 10918442; DOI: 10.1038/sj.cdd.4400700; FREE ARTICLE

Durrieu, F, K. Samejima, J.M. Fortune, S. Kandels-Lewis, N. Osheroff and W.C. Earnshaw. (2000). DNA topoisomerase IIa interacts with CAD nuclease and is involved in chromatin condensation during apoptotic execution. Curr. Biol., 10: 923-926. PMID: 10959840; DOI: 10.1016/S0960-9822(00)00620-5; FREE ARTICLE

Kirschmann, D.A., R.A. Lininger, L.M. Gardner, E.A. Seftor, A.M. Ainsztein, W.C. Earnshaw, L.L. Wallrath, and M.J.C. Hendrix. (2000). Down Regulation of HP1-Hsa Expression is Associated with the Metastatic Phenotype in Breast Cancer. Cancer Res. 60: 3359-3363. PMID: 10910038; DOI: unknown; FREE ARTICLE

Merdes, A., R. Heald, K. Samejima, W.C. Earnshaw and D.W. Cleveland. (2000). Formation of spindle poles by dynein/dynactin-dependent transport of NuMA. J. Cell Biol. 149: 851-862. PMID: 10811826; PMC2174573; DOI: 10.1083/jcb.149.4.851; FREE ARTICLE

Kaufmann, S.H. and W.C. Earnshaw. (2000). Induction of Apoptosis by Cancer Chemotherapy. Exp. Cell Res. 256: 42-49. PMID: 10739650; DOI: 10.1006/excr.2000.4838; ARTICLE

Samejima, K. and W.C. Earnshaw (2000). Differential localisation of ICAD-L and ICAD-S in cells due to removal of a C-terminal NLS from ICAD-L by alternative splicing. Exp. Cell Res. 255: 314-320.PMID: 10694446; DOI: 10.1006/excr.2000.4801; ARTICLE